| ncRNA name | rno-miR-335 |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | retinas |
| Methods | H&E staining, immunohistochemiscal staining, Western blot, microarray, qRT-PCR |
| Expression pattern | up-regulated |
| Functional description | Methane exerts protective effect on DR via anti-inflammation, which may be related to the regulatory mechanism of miRNAs. The methane treatment significantly up-regulated retinal levels of miR-192-5p (related to apoptosis and tyrosine kinase signaling pathway) and miR-335 (related to proliferation, oxidative stress and leukocyte). |
| PubMed ID | 26363454 |
| Year | 2015 |
| Title | Protective effects of methane-rich saline on diabetic retinopathy via anti-inflammation in a streptozotocin-induced diabetic rat model. |
| Drug-related ncRNA | NO |
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